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NEURONTIN (GABAPENTINA) 300 mg

Comparable a: Neurontin
Sustancia activa: Gabapentina
Concentración: 300 mg por cápsula
Presentación: Caja con 30 cápsulas
Laboratorio: PFIZER
Origen: México

Neurontin es un medicamento anticonvulsivo y neuromodulador utilizado para el tratamiento de epilepsia (como terapia adyuvante) y dolor neuropático (como neuropatía diabética o neuralgia posherpética). La gabapentina actúa modulando la actividad de los neurotransmisores en el sistema nervioso central para ayudar a reducir las convulsiones y aliviar el dolor de origen nervioso.

El consumo de este producto es responsabilidad de quien lo recomienda y quien lo usa. Consulte a su médico antes de consumir cualquier medicamento.

THERAPEUTIC INDICATIONS:

Anticonvulsant:

Epilepsy: Gabapentin is indicated as monotherapy for partial seizures, with or without secondary generalization in adults and children over 12 years.

Gabapentin is indicated as adjunctive therapy in the treatment of partial seizures with or without secondary generalization in adults and children over 3 years.

Neuropathic Pain: Gabapentin is indicated for the treatment of neuropathic pain in patients 18 years of age and older.

Contraindications Gabapentin is contraindicated in patients who have shown hypersensitivity to gabapentin or ingredients.

CAUTIONS:

General: Although there is no evidence of rebound seizures with gabapentin, the sudden interruption in the administration of anticonvulsant drugs in epileptic patients may cause status epilepticus (see DOSAGE AND ADMINISTRATION.)

In general, gabapentin is not considered to be useful for the treatment of absence seizures.

Patients who received concomitant treatment with morphine may experience increases in the concentration of gabapentin. Patients should be watched carefully because of signs of central nervous system depression, drowsiness, and the dose of gabapentin or morphine should be reduced appropriately.

Effects on ability to drive motor vehicles or use machines Patients should be advised not to drive or use potentially dangerous machinery until you know if this medication does not affect your ability to perform these activities.

RESTRICTIONS OF USE DURING PREGNANCY AND LACTATION:

Pregnancy: There have been no adequate and well controlled studies in pregnant women. Therefore, this drug should only be used during pregnancy if the potential benefit to the patient justifies the potential risk to the fetus (see PRECAUTIONS in relation to terms of carcinogenicity, mutagenicity, teratogenicity and fertility, teratogenesis).

Breast-feeding: Gabapentin is excreted in human milk. Due to the unknown effect on the infant, caution should be exercised when gabapentin is administered to mothers during lactation. Gabapentin should only be used in nursing mothers when the benefits to the mother clearly outweigh the risks to the child.

DOSAGE AND ADMINISTRATION: BAPEX is administered orally, with or without food. Thetitration is based on clinical response and plasma concentrations.

Adults and adolescents (> 12 years of age) with epilepsy: Start with 300 mg three times daily(900 mg) from the first day or 300 mg starting with the 1st. day, 600 mg the 2nd. day andending with 900 mg the third day. The dose may be increased gradually according to clinical response. The maximum interval between doses should not exceed 12 hours.

BAPEX dose in pediatric patients 3 to 12 years, will be initially 10 to 15 mg / kg / day inequally divided doses (three times a day).

The effective dose in pediatric patients aged 5 years and older after three days of graduationis 25 to 35 mg / kg / day in equally divided doses (three times a day) and patients 3 to 5 years is 40 mg / kg / day in equally divided doses (three times a day).

For adult patients with neuropathic pain, start with 900 mg / day in three doses. Adjust the dose according to response, not to exceed 3.600 mg / day.