JANSSEN-CILAG
MOTILIUM (DOMPERIDONE) 10 MG 30 TABLETS
MOTILIUM (DOMPERIDONE) 10 mg
Comparable to: Motilium
Active ingredient: Domperidone
Concentration: 10 mg per tablet
Presentation: Box with 30 tablets
Laboratory: JANSSEN-CILAG
Origin: Mexico
This medicine is used for the treatment of nausea, vomiting, and symptoms of slow gastrointestinal motility (such as feeling of fullness, bloating, and post-prandial discomfort). Domperidone works by increasing stomach and intestinal movement, facilitating digestion and reducing nausea.
The consumption of this product is the responsibility of whoever recommends it and whoever uses it. Consult your doctor before consuming any medication.
- Feeling at epigastric fullness, early satiety, feeling of abdominal distention, upper abdominal pain.
- Belching, flatulence.
- Nausea and vomiting.
- Heartburn with or without regurgitation of gastric contents into the mouth.
- Nausea and vomiting of functional origin, organic, infectious or dietetic or induced by radiation therapy or pharmacotherapy.
A specific indication is nausea and vomiting induced by dopamine agonists, such as those used in Parkinson's disease (such as L-dopa and bromocriptine).
CONTRAINDICATIONS: Motilium ® is contraindicated in the following situations:
Known hypersensitivity to domperidone or any of its excipients.
Prolactin-releasing pituitary tumor (prolactinoma).
Coadministration with oral ketoconazole, erythromycin, or other potent CYP3A4 inhibitors that prolong the QTc interval such as fluconazole, voriconazole, clarithromycin, amiodarone, and telithromycin.
Motilium ® should not be used in cases in which the stimulation of gastric motility might be dangerous, for example, gastrointestinal hemorrhage, mechanical obstruction or perforation.
CAUTIONS: When using antacids or antisecretory agents, concomitantly, they should be administered after meals and not before them, ie should not be administered simultaneously with the tablets and suspension Motilium ®.
Use Precautions: Enteric coated tablets contain lactose and may be unsuitable for patients with lactose intolerance, galactosemia, or malabsorption of glucose / galactose.
The oral suspension contains sorbitol and may be inadequate for patients intolerant to sorbitol.
Use in children: Because the metabolic and blood-brain barrier are not fully developed during the first months of life, Motilium ® as well as any medication that is administered to infants younger, should be used with caution and under close supervision care.
Since the typical absence of neurological side effects Motilium ® is due to the limited penetration through the blood brain barrier, the occurrence of these effects can not be totally excluded in babies under 1 year.
Use in hepatic impairment: Since domperidone is extensively metabolized in the liver, Motilium ® should be used with caution in patients with liver damage.
Use in renal impairment: In patients with severe renal insufficiency (serum creatinine> 6 mg/100 ml, for example,> 0.6 mmol / l) elimination half-life of domperidone is increased from 7.4 to 20.8 hours but plasma levels are lower than in healthy volunteers. Since a small amount of the drug is excreted by the kidneys, it is unlikely that the dose of a single acute dose needs to be adjusted in patients with renal failure. However, with repeated administration, frequency of administration should be reduced to once or twice daily depending on the severity of damage, and may also be necessary to reduce the dose.
Generally, patients with prolonged therapy should be reviewed regularly.
Effects on ability or use machines: Motilium ® does not affect mental alertness.
RESTRICTIONS OF USE DURING PREGNANCY AND LACTATION:
Use in pregnancy: There are limited post-marketing data on the use of domperidone in pregnant women. A study in rats has shown reproductive toxicity at high doses, is toxic to the mother. No one knows the potential risk to humans. Therefore, Motilium ® should be used during pregnancy only where justified by the anticipated therapeutic benefit.
Adults and adolescents (over 12 years and weighing 35 kg or more):
Tablets: 1 to 2 tablets of 10 mg three to four times a day, with a maximum daily dose of 80 mg.
MOTILIUM (DOMPERIDONE) 10 MG 30 TABLETS
100 in stock
MOTILIUM (DOMPERIDONE) 10 mg
Comparable to: Motilium
Active ingredient: Domperidone
Concentration: 10 mg per tablet
Presentation: Box with 30 tablets
Laboratory: JANSSEN-CILAG
Origin: Mexico
This medicine is used for the treatment of nausea, vomiting, and symptoms of slow gastrointestinal motility (such as feeling of fullness, bloating, and post-prandial discomfort). Domperidone works by increasing stomach and intestinal movement, facilitating digestion and reducing nausea.
The consumption of this product is the responsibility of whoever recommends it and whoever uses it. Consult your doctor before consuming any medication.
- Feeling at epigastric fullness, early satiety, feeling of abdominal distention, upper abdominal pain.
- Belching, flatulence.
- Nausea and vomiting.
- Heartburn with or without regurgitation of gastric contents into the mouth.
- Nausea and vomiting of functional origin, organic, infectious or dietetic or induced by radiation therapy or pharmacotherapy.
A specific indication is nausea and vomiting induced by dopamine agonists, such as those used in Parkinson's disease (such as L-dopa and bromocriptine).
CONTRAINDICATIONS: Motilium ® is contraindicated in the following situations:
Known hypersensitivity to domperidone or any of its excipients.
Prolactin-releasing pituitary tumor (prolactinoma).
Coadministration with oral ketoconazole, erythromycin, or other potent CYP3A4 inhibitors that prolong the QTc interval such as fluconazole, voriconazole, clarithromycin, amiodarone, and telithromycin.
Motilium ® should not be used in cases in which the stimulation of gastric motility might be dangerous, for example, gastrointestinal hemorrhage, mechanical obstruction or perforation.
CAUTIONS: When using antacids or antisecretory agents, concomitantly, they should be administered after meals and not before them, ie should not be administered simultaneously with the tablets and suspension Motilium ®.
Use Precautions: Enteric coated tablets contain lactose and may be unsuitable for patients with lactose intolerance, galactosemia, or malabsorption of glucose / galactose.
The oral suspension contains sorbitol and may be inadequate for patients intolerant to sorbitol.
Use in children: Because the metabolic and blood-brain barrier are not fully developed during the first months of life, Motilium ® as well as any medication that is administered to infants younger, should be used with caution and under close supervision care.
Since the typical absence of neurological side effects Motilium ® is due to the limited penetration through the blood brain barrier, the occurrence of these effects can not be totally excluded in babies under 1 year.
Use in hepatic impairment: Since domperidone is extensively metabolized in the liver, Motilium ® should be used with caution in patients with liver damage.
Use in renal impairment: In patients with severe renal insufficiency (serum creatinine> 6 mg/100 ml, for example,> 0.6 mmol / l) elimination half-life of domperidone is increased from 7.4 to 20.8 hours but plasma levels are lower than in healthy volunteers. Since a small amount of the drug is excreted by the kidneys, it is unlikely that the dose of a single acute dose needs to be adjusted in patients with renal failure. However, with repeated administration, frequency of administration should be reduced to once or twice daily depending on the severity of damage, and may also be necessary to reduce the dose.
Generally, patients with prolonged therapy should be reviewed regularly.
Effects on ability or use machines: Motilium ® does not affect mental alertness.
RESTRICTIONS OF USE DURING PREGNANCY AND LACTATION:
Use in pregnancy: There are limited post-marketing data on the use of domperidone in pregnant women. A study in rats has shown reproductive toxicity at high doses, is toxic to the mother. No one knows the potential risk to humans. Therefore, Motilium ® should be used during pregnancy only where justified by the anticipated therapeutic benefit.
Adults and adolescents (over 12 years and weighing 35 kg or more):
Tablets: 1 to 2 tablets of 10 mg three to four times a day, with a maximum daily dose of 80 mg.
The product inventory on our website is not updated in real time, so the stock levels shown do not reflect the actual inventory in our pharmacy and/or warehouse. We make every effort to ensure that out-of-stock products are not listed for purchase on our website, but some may appear as available due to the large number of products we carry. We strongly recommend that you check with us to confirm the availability of your medication before making your purchase.
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- We guarantee your order will ship within two business days of payment confirmation.
- If your medication is out of stock at the time of purchase, we will notify you of the updated shipping date.
- Please confirm availability before making your payment if you wish to have your order shipped the same day.
- For health and hygiene reasons, medications and personal care products cannot be returned once sold.
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For health and hygiene reasons, medicines and personal care products cannot be returned once sold.
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Your order will be shipped one day (maximum 2 days) after your payment.
- For orders within Mexico.
Your tracking number will be sent to you by email. You can track your package using the link we will send you or on the DHL, FedEx, or Afimex website, as applicable (we choose the best shipping option available at the time).
- For international shipments.
Your tracking number will be available two days after we have dropped off your package at the post office. You can track your order using the link we will send you via email or directly on the SEPOMEX website. After about three weeks, you can track it through your country's postal service.
- Shipping within Mexico:
Prices start at $169.00 pesos for packages up to 5 kg, with delivery in 2-5 business days (does not apply to extended areas).
- International Shipping
Prices start at $10.00 USD for small packages and increase based on weight and volume. Delivery times are 30-35 business days.