PREMARIN VAGINAL CREAM 43 G

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$ 1,248.51 $ 1,162.98

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PREMARIN Vaginal Cream 43 g

Comparable to: Premarin
Active ingredient: Conjugated estrogens
Presentation: Tube with 43 g of vaginal cream
Laboratory: Wyeth
Origin: Mexico

This medication is used for the treatment of vaginal symptoms associated with menopause, such as dryness, itching, and pain during sexual intercourse. Conjugated estrogens help restore the vaginal mucosa and improve tissue lubrication and elasticity.

The consumption of this product is the responsibility of those who recommend it and those who use it. Consult your doctor before consuming any medication.


THERAPEUTIC INDICATIONS: * Premarin vaginal cream is indicated for the treatment of vulvar atrophy, vaginal and vulvar kraurosis. 

Contraindications: Suspected or confirmed pregnancy (see Restrictions of use during pregnancy and lactation). 

Undiagnosed abnormal bleeding. 

Suspected or confirmed estrogen-dependent neoplasia (eg endometrial cancer, endometrial hyperplasia). 

History of active arterial thromboembolic disease (eg stroke, myocardial infarction) or deep thromboembolism (such as deep vein thrombosis, pulmonary embolism). 

Dysfunction or active liver disease or chronic. 

Known or suspected hypersensitivity to ingredients. 

GENERAL PRECAUTIONS: Systemic absorption can occur with the use of vaginal cream with ECE. It must take into account the precautions and warnings associated with the oral treatment of ECE. 

Fluid retention: Since estrogen / progestin may cause a degree of fluid retention in patients with conditions that can be influenced by this factor, such as cardiac or renal dysfunction, ensure careful observation when estrogens are prescribed. 

In the study of health and osteoporosis, progestin and estrogen (HOPE), the mean increases from baseline in serum triglycerides after one year of treatment with CEE 0.625, 0.45 and 0.3 mg compared with placebo were 34.3,30.2 , 25.1, and 10.7 respectively. 

Impaired liver function: Patients with impaired liver function may metabolize poorly estrogen / progestin. 

History of cholestatic jaundice: For patients with a history of cholestatic jaundice associated with past use of estrogen or pregnancy, caution should be exercised, and in case of recurrence, medication should be discontinued. 

DOSAGE AND ADMINISTRATION: The Administration should be cyclic (eg, three weeks of application and one week off) and only for short periods.

You must select the lowest dose that controls your symptoms and should be discontinued ifsymptoms persist.

Usual dose range: ½ to two grams a day, vaginally, depending on the severity of the condition. Ensure that the discontinuation or reduction of medication takes place at intervals of 3 to 6 months.

Concomitant progestogen: The addition of a progestin during the administration of estrogenreduces the risk of endometrial hyperplasia and carcinoma, which has been associated withlong-term use of unopposed estrogen.

Morphological and biochemical studies of endometrium suggest that you need to manage for 10 to 14 days to provide maximum maturation of the endometrium in order to eliminate anyhyperplastic alteration.

Since progestogens are administered to protect against endometrial hyperplastic changes, patients without a uterus may not need a progestin. Administration should be cyclic (eg, three weeks of treatment and rest) and only for short-term therapy.

Patients should be reevaluated periodically to determine whether treatment of the symptomsis still necessary.

The product inventory on our website is not updated in real time, so the stock levels shown do not reflect the actual inventory in our pharmacy and/or warehouse. We make every effort to ensure that out-of-stock products are not listed for purchase on our website, but some may appear as available due to the large number of products we carry. We strongly recommend that you check with us to confirm the availability of your medication before making your purchase.

  • We guarantee your order will ship within two business days of payment confirmation.
  • If your medication is out of stock at the time of purchase, we will notify you of the updated shipping date.
  • Please confirm availability before making your payment if you wish to have your order shipped the same day.
  • For health and hygiene reasons, medications and personal care products cannot be returned once sold.

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For health and hygiene reasons, medicines and personal care products cannot be returned once sold.

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Your order will be shipped one day (maximum 2 days) after your payment.

  • For orders within Mexico.

Your tracking number will be sent to you by email. You can track your package using the link we will send you or on the DHL, FedEx, or Afimex website, as applicable (we choose the best shipping option available at the time).

  • For international shipments.

Your tracking number will be available two days after we have dropped off your package at the post office. You can track your order using the link we will send you via email or directly on the SEPOMEX website. After about three weeks, you can track it through your country's postal service.

  • Shipping within Mexico:

Prices start at $169.00 pesos for packages up to 5 kg, with delivery in 2-5 business days (does not apply to extended areas).

  • International Shipping

Prices start at $10.00 USD for small packages and increase based on weight and volume. Delivery times are 30-35 business days.